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757 products scored186 ingredients explainedNo paid placement

Ingredient library

Worth knowing · Pesticide active

Insect growth regulators

Also appears on labels as: pyriproxyfen, (s)-methoprene, s-methoprene, methoprene

Insect hormone mimics, pyriproxyfen and methoprene, that act on flea eggs and larvae rather than on adult fleas.

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Where it comes from
Chemical synthesis.
Why it's in the product
Paired with an insecticide that acts on adult fleas.
Safety and toxicity
The Merck Veterinary Manual notes pyriproxyfen's low toxicity to mammals. It is flagged all the same, as a pesticide active, like every active in this aisle.

We make the longer argument about this one on the pesticide actives evidence page.

General reference, not veterinary advice. Dose, breed, and existing conditions change the answer, so talk to your vet before changing what your pet eats. Think we got this wrong? Tell us and we log it publicly.

Found in 6 scored products

Lowest scores first. Its presence here is not what drove those scores.